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This is one of the most important nutrients for healthy mitochondria and healthy energy production

Six months of voluntary wheel running significantly downregulated the expression of Ferritin, HO-1, janus kinase 1 (JAK1), signal transducer and activator of transcription 3 (STAT3), DMT1, TFR, and hepcidin in the cerebral cortex of five familial Alzheimers disease (5FAD) mice, reduced A and IL-6 levels, inhibited A plaque deposition and neuroinflammation, thereby improving neurological deficits in AD mice (Belaya et al., 2021)

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M2 macrophages secrete growth factors and anti-inflammatory cytokines that support tissue repair

L-Carnitine sits in the metabolic/energy category alongside vitamin B12 both feed mitochondrial energy production, and both have a large enough human evidence base that the dosing discussion can be specific rather than speculative