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10.1002/ptr.6054 Phytother Res

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Choice of the second agent to start alongside metformin should be based on the individual's priorities, preferences, and comorbidities [Grade D, Consensus]

its administered via injections or capsules in clinical settings.[4] It enhances fat burning, energy, insulin sensitivity, muscle preservation, and repair, while indirectly boosting NAD+ by slowing depletion.[5][23][24] Its membrane-permeable nature allows efficient cellular entry, making it suitable for therapeutic use

Expansion in obesity management, oral GLP-1 formulations, emerging market penetration, next-generation dual-agonists, and digital health integration offer significant growth opportunities