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In TJA, where the consequences of wound failure and PJI are severe, the absence of validated safety data is clinically meaningful
Heat, light, and moisture can degrade the peptide over time
Chronic GLP-2 treatment does not increase crypt-cell proliferation, and growth of the crypt-villus is reduced in intestinal epithelial-specific IGF knockout mice (Rowland et al., 2011)
ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity
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