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PloS One 12, e0182921

It has also been stated that Cbl, along with other B complex vitamins, positively affects the immune system, and deficiencies in these vitamins can decrease immune responses and T-cell proliferation [54,55,56]

The family of small Rho-GTPases, Rho, Rac and Cdc42, are important regulators of microtubule growth and stabilization [40,41,42,43,44,45,46] and are activated downstream of integrin engagement [47,48,49]