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Moving forward, Felson wrote, "it will be important to obtain data on whether semaglutide is similarly effective in persons with osteoarthritis without obesity, as well as better data on whether GLP-1 receptor agonists prevent progressive structural deterioration of the joint in osteoarthritis." This double-blind STEP-9 study was conducted at 61 sites across 11 countries starting in October 2021

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( B ) Absorbance spectra of APEX2 (5 M) in the presence or absence of H 2 O 2 (10 M) (left panel)

It has been investigated as a treatment for growth hormone deficiency and lipodystrophy, reaching phase II clinical trials that were discontinued for reasons unrelated to administration of the peptide