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3.2 CHAC2 in development and stem cell fate decision A role for CHAC2 in stem cell fate is likely, given the established importance of GSH homeostasis in differentiation and the known function of its homolog, CHAC1

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If not enough glutathione is being produced relative to the oxidative or free radical load present, then the free radicals, seeking balance, will rip holes in the neighboring cells and neuroinflammation will occur

In the second step, a standard peptide bond is formed between cysteine and glycine, catalyzed by GSH synthetase, which is encoded by the gene gshB

Chemical burns can continue damaging tissue until the causative agent is completely neutralized or removed