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Histamine receptors exist in various body cell types, glands, and organs, and symptoms can affect virtually all systems in the body

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These effects highlight ipamorelins potential as a therapeutic agent for neurodegenerative diseases by protecting neurons and reducing inflammation (9)

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In this review, the effect of peptides as gastrin, somatostatin, and ghrelin, all released by endocrine cells in the stomach, and of motilin, CCK, GLP-1, PYY and 5-HT, secreted in the duodenum, was summarized

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These findings indicate that hyperglycemia induces Mller cell ferroptosis via iron overload, lipid peroxidation and Xc - GSHGPX4 axis dysfunction, which further exacerbates neuroinflammation through microglial reactivation and impairs the BRB

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