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Moreover, using probucol (500 mg/day, P.O for 6 months) for secondary prevention in patients with CHD lowered the incidence of the patients primary endpoint (cardiovascular disease death, hospitalization rate), which may be partly due to its strong antioxidant capacity [245]
The difference with MCAS is that in mastocytosis, there is an uncontrolled increase in mast cells, which causes an excessive release of mediators
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When compared with the respective CON-fed groups, EtOH dramatically induced hepatic protein carbonylation in both WT and KO mice, albeit the levels in the KO mice remained higher than those observed in WT mice
Psychoneuroendocrinology (2019) 105:16471
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