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Gastrointestinal adverse events, including nausea, vomiting, and diarrhea, represent the most common side effects, occurring in a dose-dependent manner

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Finally, a number of inherited mutations in genes involved in carnitine shuttling and fatty acid oxidation pathways do not systematically result in carnitine depletion (such that carnitine supplementation may not help mitigate the symptoms) but lead to abnormal profiles of acylcarnitine esters in blood (35, 40)

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