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Moreover, Fer-1 treatment significantly reduced the release of profibrotic cytokines, including TGF-, CTGF, PDGFB, and FGF2, from TECs (Fig

A truly exciting era for Type 1 diabetes research uniting innovation that improves life now with the pursuit of lasting cures for tomorrow

The dose is adjusted based on severity and response to treatment

We were exploring ways of developing peptides that bind selectively, and we were very successful at that, but then we confronted the problem that our short, 23-residue peptides are not promising therapeutic candidates primarily because they cannot get into cells, Keating says

Hold off on anything intense in the target area until the cycle's done