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Older adults are also at a higher risk of B12 deficiency due to decreased stomach acid levels, which are needed to separate B12 from protein in the diet for absorption
According to the NHS, the usual pattern depends on the cause: Non-dietary cause (for example an absorption problem): an injection of hydroxocobalamin every two to three months, usually for life
Extrapolating beyond that requires mechanistic reasoning, not direct evidence
Urticaria, pruritus without rash, and angioedema have been reported in less than one percent of patients