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Methods and materials This was a double-blind clinical trial study including 110 patients with PCOS attended to Royan Institute between March 2020 and February 2023
In the SUSTAIN-6 trial [4], one of the earliest extensive cardiovascular outcome studies, semaglutide significantly reduced the risk of new or worsening nephropathy, defined as persistent macroalbuminuria, doubling of serum creatinine, need for RRT, or death from renal causes, compared with placebo (3.8% vs 6.1%
report that over 80 peptides are currently available on the market worldwide, and approximately 170 and 150 more are in clinical development or preclinical evaluation, respectively (1)
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Acknowledgements The Section of Endocrinology and Investigative Medicine is funded by grants from the MRC, BBSRC, NIHR, an Integrative Mammalian Biology (IMB) Capacity Building Award, an FP7-HEALTH-2009-241592 EuroCHIP grant and is supported by the NIHR Biomedical Research Center Funding Scheme
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