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633 The degree to which pentostatin inhibits adenosine deaminase varies among cell types, possibly because of differences in enzyme inhibitor dissociation constants in different cells as well as differences in cellular accumulation of the drug
Mingrone G et al
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Ok CY, Salim AA, Loghavi S, Rajyalakshmi L, Routbort MJ, Singh RR, Zuo Z, Pierce S, Garcia-Manero G, Kantarjian HM, Cortes JE, Ravandi F, Andreeff M , Medeiros LJ, Patel KP
Recent advances in nanotechnology have yielded multifunctional platforms incorporating GSH-responsive linkages, redox-active metals, and prodrug designs with strong promise for targeted delivery and theranostics
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