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Levels of autophagy have been shown to decrease with age (Simonsen et al., 2008)

This result eliminates the possibility that the survivors of the high temperature (42 O C) in the first experiment a are either heat-tolerant mutants or persistor-like cells that behave similarly to persistors of antibiotic treatments

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In contrast, genetic or pharmacological inhibition of lipid peroxidation by GPX4 overexpression significantly decreased RSL3/BV6-induced cell death