"L-carnitine exerts a nutrigenomic effect via direct modulation of nuclear receptor signaling in adipocytes, hepatocytes and SKMC, demonstrating its nutritional impact." Nutrition Research , January 2021, Jeukendrup, A E et al
The current study encompassed all cases in which GLP-1RAs were administered and listed as primary suspect drugs, secondary suspect drugs, or concomitant drugs for SSIBs
More serious but rare complications include pancreatitis and gallbladder disease
Novo Nordisk's Rybelsus showed that transcellular gastric absorption, boosted with SNAC, can partially get around the first two problems, but cannot solve the third
Remember that you know your body best, and unexpected or changing symptoms during perimenopause deserve serious attention