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In a meta-analysis, subcutaneous semaglutide demonstrated superior efficacy in reducing glycated hemoglobin when compared to other antidiabetic drugs, without increasing the rate of hypoglycemia

Default days supply = 30 for GLP1s and 90 for metformin

doi:10.1161/CIRCRESAHA.114.303772 62

General hydration recommendations align with NHS guidance: adults should aim for approximately 68 glasses (1.21.5 litres) of fluid daily , though individual needs vary based on body size, activity level, climate, and concurrent medical conditions

38 Low vitamin D has also been linked to worsening of sleep apneas negative effect on heart disease risk