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Specific and moderate manipulation of activities of LOXs and transcriptional regulation of hypoxia-responsive transcription factors through copper bioavailability modulation or continuous hypoxia-conditioning may become effective interventions for enhanced cartilage regeneration, as well as promising rejuvenation therapeutics, which may exert further therapeutic implications in the upcoming clinical arena

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Nutritional psychiatry: The present state of the evidence

H., Brown-Frandsen, K., et al