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Mice that received 21 days of vehicle or tirzepatide q.o.d., following 12 weeks of control or DIO diet, were challenged with MC38 cancer cells, continued their assigned diet and drug intervention, and were then euthanized after 14 days of tumor growth

At high concentrations where dead space losses are meaningful, this simple technique recovers drug that would otherwise stay trapped in the hub

While these reactions are not extremely common, they do occur in a notable number of cases

The agency also cited concerns over quality, safety, and potential violations of the Federal Food, Drug and Cosmetic Act