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In other words, this initial stage was less about immediate outcomes and more about building a stable foundation for the higher doses that followed

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It is influenced by genetics, hormones, immune activity, oxidative stress, and chronic inflammation

Even though traditional methods are meant to work, they often fail because they are difficult to understand or follow

4 Challenges and future directions 4.1 Safety considerations The safety profile of dual or triple receptor agonists targeting GLP-1, GIP, and GCG receptors in the treatment of MASLD and related metabolic disorders warrants careful evaluation