Notably, discordant results among various assays were observed in the CAP survey, consistent with findings from earlier studies
However, self-medication or excessive treatment may increase the risk of the side effects of glutathione injection, including allergic reactions, digestive discomfort, and skin sensitivity
In doxorubicin -induced cardiomyopathy models, HS induces S-sulfhydration of KEAP1, promoting NRF2 nuclear translocation and activating the SLC7A11/GSH/GPx4 axis to reduce lipid peroxidation, with efficacy directly correlated with ferroptosis inhibition (Zhang et al., 2024)
Kristensen, E
It also explains why the final FDA response matters: the committee did not reach anything close to consensus, and FDAs own scientific review remained negative