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The decreased blood and liver levels of EtOH and AA in WT in KO mice chronically fed EtOH may relate to delayed gastric emptying and/or increased gastric mucosal of EtOH-metabolizing enzymes
This is when tracking becomes especially valuable
Reasons for the discrepancies may relate to the dose of curcumin and the chemotherapeutic agent
IV administration allows for much higher blood concentrations than oral supplements (up to 80 mg/dl vs
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