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These SCFAs activate free fatty acid receptors (FFAR2 and FFAR3) on intestinal L-cells, directly stimulating GLP-1 secretion
Treatment with the multi-agonists caused a very significant reduction in body weight during the 72-h treatment period, which was more pronounced in mice treated with GLP1/GIP/Glucagon (Fig
Furthermore, in a maize cultivar with symptomless SCMV-resistance, a proteomic analysis revealed a down-regulation of two different GSTs in later phases of virus infection, pointing to a role of GSTs in establishing virus resistance at the early stages of pathogenesis (Wu et al., 2013a,b)
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