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Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue, first described by Raun and colleagues in 1998 as the first selective growth hormone secretagogue. It remains one of the most extensively characterised compounds of its class in the published research literature
Some also notice subtle changes in appetite, which is an early sign that semaglutide is engaging hungerregulating pathways
In some contexts it is suggested that it could support mitochondrial function or neuronal signalling, but the clinical evidence is heterogeneous and does not allow generalisation of benefits to the whole population
Gastroparesis is a serious medical condition where the stomachs muscles slow down or stop working properly
Science 317 (5839), 807810
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