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81 NezuJ.TamaiI.OkuA.OhashiR.YabuuchiH.HashimotoN.et al (1999)

Even though extensive research conducted over the last years did not unequivocally establish the etiology of depression, it revealed the complexity of its pathogenesis

However, it is important to note that the vast majority of this data comes from animal models, and human clinical trial data remains limited

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