They are now commonly used when: Metformin alone is no longer enough Weight gain is contributing to worsening glucose control There is a need to minimise hypoglycaemia risk Someone has existing cardiovascular disease or multiple risk factors For many people, GLP-1 therapy can delay or reduce the need for insulin, or allow insulin doses to be kept lower and safer
Oxidative stress: Signaling pathways, biological functions, and disease
They work by mimicking a hormone called glucagon-like peptide-1, which your body naturally produces after eating
Tan M, Lamendola C, Luong R, McLaughlin T, Craig C
Consistent with the known effects and common side effects of semaglutide, more participants receiving active medication reported decreased appetite as well as increased nausea and constipation