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Rosenstock stated in the Regeneron press release: These complete 26-week COURAGE results demonstrate a meaningful opportunity to preserve muscle mass while enhancing fat loss. Also noted: Numerical improvements in metabolic and lipid parameters, secondary and exploratory endpoints, were seen across all treatment groups, including improvements in waist circumference, blood pressure, cholesterol, triglycerides and A1C. Read the full press release:
Vitamin B12 supplementation deserves specific mention because GLP-1 medications can reduce B12 absorption over time by altering gastric acid production and gut motility
This delays gastric emptying, keeping you full for longer and helping control portions naturally
Changes in bile acid handling and shifts in gut bacteria after starting the drug also show up in some people as diarrhea
When the body enters a sustained calorie deficit on a GLP-1 receptor agonist, fat is mobilised from every depot in proportion, and the face is no exception
