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The expression of nutrient transporters, such as GLUT1 and LAT1, has been shown to be high in both, the BBB and in glioma (207, 208), which led to the development of different transporter-utilizing anti-cancer drug delivery strategies in order to reach the cancer cells residing beyond the intact BBB (Table II)

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Understanding GLP-1: The First Target GLP-1 became the first incretin targeted for pharmaceutical development, leading to medications like exenatide, liraglutide, and eventually semaglutide