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Recently discovered S-nitroso metabolites generated in-vivo from GSH and NO (Nitric Oxide) further diversity GSHs impact on metabolism

The findings suggest potential therapeutic interventions through targeting upregulated pathways involved in glycolysis and NO signaling to impede polyp growth, while strategies aimed at restoring EZR function may help maintain proper bile composition and mitigate the risk of gallbladder diseases

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Mao L, Hochstetter D, Yao L, Zhao Y, Zhou J, Wang Y, et al