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Recent studies by Sanofi-Aventis and Eli Lilly in phase 1 and 2, respectively, were the first to report and have stimulated further interest in the field

Retatrutide (also known as LY3437943) is an investigational medication developed by Eli Lilly that activates three key metabolic receptors : GLP-1 (glucagon-like peptide-1): reduces appetite and improves blood sugar control GIP (glucose-dependent insulinotropic polypeptide): enhances insulin response Glucagon receptor: increases energy expenditure and fat metabolism This triple-hormone weight loss drug approach creates a balanced effect, suppressing hunger and increasing calorie burn, something earlier GLP-1 medications couldnt fully achieve

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