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At 52 weeks, semaglutide-treated patients saw a mean improvement of 16.6 points in their scores on the Kansas City Cardiomyopathy Questionnaire (KCCQ), a validated measure of heart failure-related symptoms and physical limitations, compared with an 8.7-point improvement in the placebo group

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A total of 1961 adults with a body-mass index (BMI) of 30 or above (or 27 in individuals with at least one weight-related medical condition) and without diabetes were enrolled in the study