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Randomized phase II study evaluating palbociclib in addition to letrozole as neoadjuvant therapy in estrogen receptor-positive early breast cancer: PALLET trial
In addition, mitochondrial transferrin mitoferrin 1/2 is destroyed on the inner mitochondrial membrane, which consequently results in abnormal iron metabolism in the mitochondria (39)
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Therefore, based on summaries of the research regarding the relationship between breast cancer and GPxs, this article focused on the molecular mechanism and function of different GPxs and their diverse roles in the occurrence and development of breast cancer, further clarifying the pathogenesis of breast cancer and providing a potential direction for further studies on the treatment of breast cancers
