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Scientific Background on TB-500 (Thymosin Beta-4 Fragment) TB-500 is the synthetic heptapeptide fragment (Ac-LKKTETQ-NH) of the naturally occurring 43-amino-acid protein Thymosin Beta-4 (T4)
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The CAS registry number 137525-51-0 and PubChem CID 9941957 are the canonical chemical identifiers
DMF mediates NRF2-dependent and independent mechanisms on TSS pathway CBS activation DMF activates NRF2, the master regulator for the antioxidative stress response, to regulate the expression of proteins involved in iron hemostasis, and GSH synthesis such as HMOX1, NQO1, FTH, FTL, SLC40A1 in a variety of cellular systems 37
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