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doi: 10.1101/cshperspect.a000158 87 DbekJKuachAGsiorZ

Blood, 112(6), pp.2214-2221

Causes and Symptoms of B12 Deficiency Deficiency can arise from: Poor dietary intake Malabsorption issues (e.g., pernicious anemia, atrophic gastritis) Gastrointestinal surgeries or disorders (e.g., Crohns disease) Certain medications affecting stomach acid or absorption Symptoms of deficiency include fatigue, weakness, numbness or tingling in hands and feet, memory difficulties, mood changes, and in severe cases, neurological damage

Eosinophils are a major source of nitric oxide-derived oxidants in severe asthma: characterization of pathways available to eosinophils for generating reactive nitrogen species

This makes it much faster and more reliable especially for people who cannot absorb B12 properly through food or supplements