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Blood samples for pharmacokinetic analysis were collected up to 15 min pre-dose (day 1), and at 4, 8, 12, 18, 24, 30, 36, 48, 54, 60, 72, 84, 96 and 120 h post-dose
Published animal studies using BPC-157, including those extending across multiple weeks of daily administration, have not documented tumor formation or accelerated malignant growth as an observed outcome
PMID:11115795
Consequently, active transporters located in the abluminal side of the BBB export AAs from the brain into the endothelial cell, to keep the lower concentration found in the extracellular fluid
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