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Relative contraindications requiring caution include active or suspected cancer (GHK-Cu promotes angiogenesis with concern about theoretically feeding tumors, though conflicting data shows documented anti-cancer gene expression effects requiring medical supervision), severe organ dysfunction (kidney or liver failure may slow peptide clearance), hemochromatosis or copper overload conditions, autoimmune disorders, and patients on immunosuppressants or blood thinners

Some people with heart disease may already have poor circulation to the brain, which makes dizziness more likely

Serious Adverse Events Seizures: There have been reports of increased seizure frequency in patients with a pre-existing seizure disorder

The Science Behind Lumi Eye Treatments The active ingredient, polynucleotide PDRN, regenerates damaged tissues, restores volume, and smooths the skin while deeply moisturising

Comparative Trials Head-to-head data suggest tirzepatide (Zepbound) achieved ~20.2% mean weight loss at 72 weeks versus ~13.7% with semaglutide (Wegovy)