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We conclude that E2 directly controls both - and L cells to increase GLP-1 secretion, in addition to its effects on insulin and glucagon secretion, highlighting the potential beneficial role of the estrogenic pathway and, more particularly, of ER agonists to prevent type 2 diabetes
6ad and S3)
Very rarely, it may be the cause coming from the lower small bowel or upper large bowel
The synergistic activation of GIP and GLP-1 receptors has been recognized as a promising therapeutic approach in the treatment of T2D and obesity (17, 18)
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