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Approach stacks as exploratory and proceed carefully until robust human data emerge

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Glutathione S-transferases of 28kDa as major vaccine candidates against schistosomiasis

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In the absence of intracellular cystine, the activity of mTORC1 will be inhibited and the amount of mTORC1 localized to lysosomes will be decreased, thereby reducing the level of intracellular GPX4