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The debate often boils down to two campslocalized versus systemic application
L-carnitine can be given with or without food, but giving it with food can decrease the risk of digestive upset
Modestly higher homocysteine, as predicted by genetics, was associated with an increased risk of stroke .[ref] High homocysteine levels can damage the endothelium (lining of the blood vessels) and cause hardening of the arteries.[ref] Related article : Heart disease genes Chronic diseases: Similarly, MR studies have shown that high homocysteine can cause metabolic syndrome , worsen osteoarthritis , increase the risk of cataracts, and increase the risk of Alzheimers disease
Transdermal gels and creams (both FDA-approved and compounded), vaginal preparations for genitourinary symptoms, sublingual troches, and injectable estradiol are all available
2005 Jul 20;(3):CD004655
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