semaglutide makes me feel awful If you are noticing an effect on your mood while using a GLP-1 medication, here's what might be at play Dermal Hypersensitivity Reaction to Semaglutide:

Research Use Only: This product is intended for laboratory research use only and is not for human consumption, diagnostic, or therapeutic use

Are there any side effects of GLP-1 weight loss shots

Severe cramps accompanied by swelling, redness, warmth, weakness, dark urine, fainting, chest pain, or shortness of breath require prompt medical attention

Some users report that abdominal injections of tirzepatide or semaglutide produce stronger initial nausea compared to thigh injections, likely because of this faster absorption profile

In people with T2D, retatrutide (0.5 to 12 mg) led to substantial reductions in bodyweight and HbA1c compared to both placebo and dulaglutide 1.5 mg in a phase 2 trial [67]