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In this study, a mean increase in 24-h HR of 3.6 and 3.5 bpm was observed at weeks 14 and 30, respectively
Another important difference lies in the interpretation of risk and benefit
The clinical benefits, including reductions to hospitalizations due to MACE continue to be observed in the second analysis
They ingested increasing doses of niacin (250-1000 mg daily) for 16 weeks as described previously 15 , and the blood samples were taken in different timepoints during the supplementation
Phase 3 trials recruit differently, run differently, and aren't directly comparable
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