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Native IGF-1 produced by the liver in response to growth hormone binds immediately to six different IGF-binding proteins (IGFBP-1 through IGFBP-6), which reduces free circulating IGF-1 to less than 1% of total serum levels
bioRxiv , 2021.2009.2028.462109 (2021)
It was previously found to be an extremely important intracellular degradation site, serving as the terminal destination during phagocytosis and autophagy 2
For a compound like AHK-Cu that's biologically active at picomolar to nanomolar concentrations, the difference in efficacy between 98% and 99% pure preparations is likely small
Consistency Matters While timing can enhance supplement effectiveness, consistency is key
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