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Copper peptides should be avoided by anyone with a known copper allergy, those with active inflammatory skin conditions like a rosacea flare or severe eczema, anyone whose skin barrier is severely compromised, and (until more research is available) those who are pregnant or breastfeeding

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N Engl J Med 373(23):22472257 Muskiet MHA, Tonneijck L, Huang Y, Liu M, Saremi A, Heerspink HJL et al (2018) Lixisenatide and renal outcomes in patients with type 2 diabetes and acute coronary syndrome: an exploratory analysis of the ELIXA randomised, placebo-controlled trial

If you see a dsip peptide dosage chart that gives one number for everyone, that is a warning sign