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In stressed cells NRF2 is released and taken from the cytoplasm into the nucleus by karyopherins (Theodore et al., 2008

Those points must be evaluated from the applicable specification and batch information

Carcinogenesis 29:102232 Natarajan VT, Singh A, Kumar AA (2010) Transcriptional upregulation of Nrf2-dependent phase II detoxification genes in the involved epidermis of vitiligo vulgaris

FMT requires comprehensive donor screening (including MDROs), validated processing with chain-of-custody and retention samples, release criteria, and pharmacovigilance