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The only direct head-to-head trial comparing tirzepatide and semaglutide (SURMOUNT-5) was conducted in individuals with obesity without T2DM and evaluated maximum tolerated doses rather than the full range of clinically relevant dosing strategies [8]

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In evoke and evoke+, the safety and tolerability of semaglutide will be assessed in a population of individuals with AD aged 5585 years old

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