Studies have shown that system xCT was mainly located in tubular cells, and its inhibition resulted in a rapid decline in GSH levels, which may accelerate AKI (Su et al., 2019)
View Abstract [6] Hagen TM, Wierzbicka GT, Sillau AH, Bowman BB, Jones DP
However, cellular GSH concentrations vary according to various conditions, which can affect the in vitro function and therapeutic efficacy of MSCs [8]
Salidroside has also proved its beneficial effect in the paraquat-induced rat ALI model (Zhang et al., 2014
(2001) investigated AOD9604 in obese Zucker rats and observed that chronic administration was associated with reduced body weight gain without changes in IGF-1 levels or glucose tolerance, distinguishing its activity profile from that of full-length growth hormone [1]