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While cobalamin overdose is unheard of because it is non-toxic and water-soluble, cobalamin deficiency can happen due to a number of reasons, including certain diseases and genetic defects.
30 Vegans and strict vegetarians should be counseled to consume fortified cereals or supplements to prevent deficiency
HbA1c reductions of 1.5-2.5 percentage points are common
IGF-1 LR3 is not FDA-approved for human use and is prohibited by WADA in competitive sports
Furthermore, IM administration of hydroxocobalamin is also the preferred treatment for pediatric patients with intrinsic cobalamin metabolic diseases
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