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Duration: Continue as long as both are beneficial

Cell Rep 17: 2845-2856, 2016

Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95

In this regard, the mitochondria-targeted SOD mimetic Mito-tempo has been shown to protect against APAP hepatotoxicity, while Tempo, which exhibits SOD activity but without its specific mitochondrial targeting, failed to protect against APAP-induced liver injury ( - generation in APAP hepatotoxicity