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(2022) use zebrafish, cochlear hair cells, and HEI-OC1 cells as in vitro and in vivo models to evaluate eupatilins antioxidant and anti-apoptotic capabilities in the setting of cisplatin-induced ototoxicity
those pathways mentioned above include inositol-requiring enzyme 1 (IRE1), the protein kinase RNA (PKR)-like ER kinase (PERK), and the activating transcription factor 6 (ATF6) which remain inactive by attaching to binding immunoglobulin protein (BiP), also known as 78-kDa glucose-regulated protein (GRP78) conditions [9093]
*FUENTE SOBRE SEMAGLUTIDE ORAL USADO PARA ADELGAZAR: New England Journal of Medicine
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