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Tirzepatide population pharmacokinetics and exposure Schneck 19-study pooled popPK (CL/F 0.061 L/h, half-life 5.4 d, accumulation 1.7x, body-weight covariate +22% at 70 kg / -33% at 120 kg)
Orforglipron is a novel, oral, once-daily G protein-biased non-peptidic GLP1RA that resulted in impressive weight loss over a short-period in a phase II trial in people with obesity
They definitely made the long infusion days more pleasant
May help maintain gut and digestive health
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