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Another study demonstrated that minerals, antioxidants, and fiber showed no significant differences between fresh and frozen fruits and vegetables for the majority of those tested, indicating that freezing does not inherently degrade these essential nutrients (Bouzari et al., 2015)

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Further support for a direct contribution of glutamate in the disease process came from blocking studies, applying Memantine, an N-methyl-D-aspartate (NMDA) ionotropic glutamate receptor antagonist

However, they are all meant to address different purposes